Neosordarin and hydroxysordarin, two new antifungal agents from Sordaria araneosa.
نویسندگان
چکیده
Two novel antifungal agents belonging to the sordarin family have been isolated from fermentations of Sordaria araneosa by bioassay-guided purification and their structures elucidated by NMR techniques. Neosordarin (1) is closely related to the recently discovered hypoxysordarin (2), with only small differences on the aliphatic side chain acylating the hydroxyl in the 3'-position of the sordarose moiety. Hydroxysordarin (3) closely resembles sordarin (4), the only slight difference being the replacement of sordarose with altrose as the sugar unit.
منابع مشابه
Hypoxysordarin, a new sordarin derivative from Hypoxylon croceum.
Hypoxysordarin (1), a new sordarin derivative, was isolated from the fermentation broth of the facultative marine Hypoxylon croceum together with a new gamma-lactone, hypoxylactone (2) and sordarin (3). The structures were determined by spectroscopic methods. Sordarin (3) has previously been isolated from the terrestrial Sordaria araneosa (Sordariaceae). Like the parent compound hypoxysordarin ...
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ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 55 4 شماره
صفحات -
تاریخ انتشار 2002